The primary focus of our laboratory is to quantitatively describe the structure and function of active local neocortical microcircuits in motorĀ and visual cortex. Local connectivity is a critical factor controlling the flow of information in the neocortex, and changing synaptic strength of individual connections is the leading candidate for the instantiation of learning. By studying the neocortex at the scale of local microcircuits composed of hundreds of neurons and their corresponding connections, we are able to bridge observational scales, connecting insights about single synapses all the way to behaving animals. We emphasize interdisciplinary training combining experiment, modeling, and theory.

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